PPH – Perfect Phylogeny Haplotyping

PPH

:: DESCRIPTION

PPH (Perfect Phylogeny Haplotyper based on graph realization ) is a program for inferring haplotypes from genotypes to determine if there are resulting haplotypes that fit a tree model (i.e. a perfect phylogeny, a coalescent). In more population genetic terms, PPH determines whether a set of SNP genotypes can be explained by haplotype pairs that could have evolved on a coalescent under the no-recombination, infinite sites model. Hence it determines for SNP genotype data what the three or four gametes test (depending on whether the tree is rooted or not) determines for haplotype data.

::DEVELOPER

Dan Gusfield’s group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/Windows/MacOsX

:: DOWNLOAD

  PPH

:: MORE INFORMATION

Citation

Ren Hua Chung and Dan Gusfield
Perfect Phylogeny Haplotyper: Haplotype Inferral Using a Tree Model
Bioinformatics (2003) 19 (6): 780-781.