PGA v2.0.4

:: DESCRIPTION

PGA is a Java and Perl-based application with a command line interface for post-GWAS (Genome-wide association studies) analysis. The application incorporates gene regulatory information in producing a list of scored candidate disease genes from a set of GWAS-reported variants, where candidate scores indicate the strength of a gene’s relationship to the disease in question.

::DEVELOPER

ZDZ lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux /Windows / MacOsX
Java
Perl

:: DOWNLOAD

PGA

:: MORE INFORMATION

Citation

Lin JR, Jaroslawicz D, Cai Y, Zhang Q, Wang Z, Zhang ZD.
PGA: post-GWAS analysis for disease gene identification.
Bioinformatics. 2018 May 15;34(10):1786-1788. doi: 10.1093/bioinformatics/btx845. PMID: 29300829; PMCID: PMC5946835.

PGA

:: DESCRIPTION

PGA (Power for Genetic Association Analyses)is a package of algorithms and graphical user interfaces developed in Matlab for power and sample size calculation under various genetic models and statistical constraints. The software is designed to facilitate decision making for case-control association studies of candidate genes, fine-mapping studies, and whole-genome scans.