GeneDesign 5.54 – Codon Manipulation for ORFs

GeneDesign 5.54

:: DESCRIPTION

GeneDesign is a codon manipulation library. Its main purpose is to ease the design and assembly of synthetic DNA.

::DEVELOPER

Joel Bader lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

 GeneDesign

:: MORE INFORMATION

Citation

Design-A-Gene with GeneDesign.
Richardson SM, Liu S, Boeke JD, Bader JS.
Methods Mol Biol. 2012;852:235-47. doi: 10.1007/978-1-61779-564-0_18.

BALBOA – Extension of Bicluster Analysis to allow for the Functional Classification of ORFs

BALBOA

:: DESCRIPTION

BALBOA is an ORF (Open Reading Frame) annotation approach, in which classifiers are constructed from the class specific expression patterns discovered by bicluster analysis. Firstly a set of bicluster classifiers is build using a labelled training set from the annotated ORFs in the expression data. These biclusters are then used to classify an unlabelled ORF set i.e. the unannotated ORFs from the expression dataset.

::DEVELOPER

the Machine Learning Group (MLG)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows /Mac OsX
  • Java

:: DOWNLOAD

 BALBOA

:: MORE INFORMATION

Citation

BMC Genomics. 2008 Sep 16;9 Suppl 2:S20.
Extending bicluster analysis to annotate unclassified ORFs and predict novel functional modules using expression data.
Bryan K, Cunningham P.