Tag: Mutational Cluster

GraphPAC 1.34.0 – Identification of Mutational Clusters in Proteins via a Graph Theoretical Approach

GraphPAC 1.34.0

:: DESCRIPTION

GraphPAC is a bioconductor R package for identifying mutational clusters of amino acids in a protein while utilizing the protein tertiary structure via a graph theoretical model.

::DEVELOPER

Zhao Hongyu’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 GraphPAC

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2014 Mar 26;15(1):86. [Epub ahead of print]
A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations.
Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H.

QuartPAC 1.16.0 – Identification of Mutational Clusters in Protein Quaternary Structures

QuartPAC 1.16.0

:: DESCRIPTION

QuartPAC (Quaternary Protein Amino acid Clustering) is a novel methodology, that identifies non-random mutational clustering while utilizing the protein quaternary structure in 3D space.

::DEVELOPER

QuartPAC team

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R / BioConductor

:: DOWNLOAD

 QuartPAC

:: MORE INFORMATION

Citation

Leveraging protein quaternary structure to identify oncogenic driver mutations.
Ryslik GA, Cheng Y, Modis Y, Zhao H.
BMC Bioinformatics. 2016 Mar 22;17(1):137. doi: 10.1186/s12859-016-0963-3.