CoMDP – Co-occurring Mutated Driver Pathway

CoMDP

:: DESCRIPTION

CoMDP is a package for de novo identifying co-occurring driver pathways in cancer with mutation data.

::DEVELOPER

Shihua Zhang’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux
  • MatLab

:: DOWNLOAD

 CoMDP

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2014 Aug 9;15:271. doi: 10.1186/1471-2105-15-271.
Discovery of co-occurring driver pathways in cancer.
Zhang J, Wu LY, Zhang XS, Zhang S.

MDPFinder – Mutated Driver Pathway Finder

MDPFinder

:: DESCRIPTION

MDPFinder is a package for identifying driver pathways promoting cancer proliferation and filtering out the unfunctional and passenger ones.

::DEVELOPER

Shihua Zhang’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux
  • MatLab

:: DOWNLOAD

 MDPFinder

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Nov 15;28(22):2940-7. doi: 10.1093/bioinformatics/bts564. Epub 2012 Sep 14.
Efficient methods for identifying mutated driver pathways in cancer.
Zhao J, Zhang S, Wu LY, Zhang XS.

Dendrix 0.3 – Discovery of Mutated Driver Pathways in Cancer

Dendrix 0.3

:: DESCRIPTION

Dendrix (De novo Driver Exclusivity) is an algorithm for discovery of mutated driver pathways in cancer using only mutation data. It finds sets of genes, domains, or nucleotides whose mutations exhibit both high coverage and high exclusivity in the analyzed samples.

::DEVELOPER

Raphael Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 Dendrix

:: MORE INFORMATION

Citation:

F. Vandin, E. Upfal, B.J. Raphael. (2011)
De novo Discovery of Mutated Driver Pathways in Cancer.
Genome Res. 2011 Jul 11