mSD
:: DESCRIPTION
mSD (motif-guided sparse decomposition) identifies gene regulatory modules by integrating gene expression data and DNA sequence motif information. The mSD approach is implemented as a two-step algorithm comprising estimates of (1) transcription factor activity and (2) the strength of the predicted gene regulation event(s).
::DEVELOPER
Computational Bioinformatics & Bio-imaging Laboratory (CBIL)
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Windows
- MatLab
:: DOWNLOAD
:: MORE INFORMATION
Citation:
BMC Bioinformatics. 2011 Mar 22;12:82.
Motif-guided sparse decomposition of gene expression data for regulatory module identification.
Gong T, Xuan J, Chen L, Riggins RB, Li H, Hoffman EP, Clarke R, Wang Y.