Tag: Model-free Analysis

FASTEH+ / FASTEHPLUS – Model-free Analysis and Permutation Test(s) of Allelic Association

FASTEH+ / FASTEHPLUS

:: DESCRIPTION

FASTEHPLUS performs model-free analysis and permutation test(s) of allelic association based on EH  and EHPLUS (Zhao et al.2000). It uses marker genotypes from a group of unrelated individuals or a group of cases and a group of controls and employs gene-counting algorithm to estimate haplotype frequencies and output asymptotic and permutation test statistics. As yet it does not handle missing genotypes. Please check for GENECOUNTING program on this site if you wish to use individuals with missing genotypes in your analysis.

::DEVELOPER

Jing Hua Zhao

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • linux/Windows/

:: DOWNLOAD

 FASTEHPLUS

:: MORE INFORMATION

Citation

Zhao, J. H., Sham, P. C. (2002)
“Faster allelic association analysis using unrelated subjects“.
Human Heredity, 53(1), 36-41.

EH+ / EHPLUS 2.0 – Model-free Analysis and Permutation tests for Allelic Association

EH+ / EHPLUS 2.0

:: DESCRIPTION

EHPLUS is a modified version of EH which only uses counts of genotypes that are actually observed. Each row of the data file consists of an identifying number for the genotype in question together with counts of the number of times it occurs in cases and controls. The genotype number is calculated in a similar way as for the original EH, and this number is produced automatically by PMPLUS, a program which accepts input files in the same format as PM but which outputs data in the format to be used by EHPLUS. EHPLUS also has a special method for handling memory requirement, which means that it can successfully deal with far more possible haplotypes than EH.

::DEVELOPER

Jing Hua Zhao

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • linux/Windows/

:: DOWNLOAD

  EHPLUS

:: MORE INFORMATION

Citation

Zhao, Curtis, Sham (2000),
“Model-free and permutation tests for allelic associations“,
Human Heredity, 50(2):133-139.