miES – Predict microRNA Essentiality Score

miES

:: DESCRIPTION

miES is a tool to predict the essentiality or importance of miRNAs with machine learning and sequence features.

::DEVELOPER

the Cui Lab

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Windows/Linux
  • R

:: DOWNLOAD

miES

:: MORE INFORMATION

Citation

Song F, Cui C, Gao L, Cui Q.
miES: predicting the essentiality of miRNAs with machine learning and sequence features.
Bioinformatics. 2019 Mar 15;35(6):1053-1054. doi: 10.1093/bioinformatics/bty738. PMID: 30165607.

sTAM – Single Sample microRNA Set Enrichment Analysis

sTAM

:: DESCRIPTION

sTAM is a computational tool for single sample miRNA set enrichment analysis (MSEA).

::DEVELOPER

the Cui Lab

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

NO

:: MORE INFORMATION

Citation

Shi J, Cui Q.
sTAM: An Online Tool for the Discovery of miRNA-Set Level Disease Biomarkers.
Mol Ther Nucleic Acids. 2020 Sep 4;21:670-675. doi: 10.1016/j.omtn.2020.07.004. Epub 2020 Jul 10. PMID: 32750560; PMCID: PMC7398894.

MIReStruC 1.0 – A tool to find microRNA Structural Clusters

MIReStruC 1.0

:: DESCRIPTION

MIReStruC (miRNA Structural Cluster) is a tool to find microRNA structural clusters at genome scale and from deep sequencing data.

::DEVELOPER

Laboratory of Computational and Quantitative Biology(LCQB)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python
  • C Compiler

:: DOWNLOAD

 MIReStruC

:: MORE INFORMATION

Citation

A. Mathelier and A. Carbone. (2013)
Large scale chromosomal mapping of human microRNA structural clusters
Nucleic Acids Research. 10.1093/nar/gkt112

miR2Gene 201107 – Gene Pattern discovery by Enrichment Analysis of their microRNA Regulators

miR2Gene 201107

:: DESCRIPTION

miR2Gene for gene pattern discovery by enrichment analysis of their microRNA regulators is a web-accessible program, which is used to mine potential patterns for one single gene, multiple genes, and KEGG pathway genes based on miRNA set enrichment analysis of the miRNAs regulating given genes.

::DEVELOPER

the Cui Lab

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Syst Biol. 2011 Dec 14;5 Suppl 2:S9. doi: 10.1186/1752-0509-5-S2-S9. Epub 2011 Dec 14.
miR2Gene: pattern discovery of single gene, multiple genes, and pathways by enrichment analysis of their microRNA regulators.
Qiu C1, Wang J, Cui Q.

miRQuest – Integration of tools on a Web Server for microRNA Research

miRQuest

:: DESCRIPTION

miRQuest is a webserver that enables to the end-user a friendly and standardized software to use the many ab initio tools for miRNA investigation.

::DEVELOPER

miRQuest team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

miRQuest: integration of tools on a Web server for microRNA research.
Aguiar RR, Ambrosio LA, Sepúlveda-Hermosilla G, Maracaja-Coutinho V, Paschoal AR.
Genet Mol Res. 2016 Mar 28;15(1). doi: 10.4238/gmr.15016861.

RNA22 v2 – microRNA Target Detection

RNA22 v2

:: DESCRIPTION

RNA22 finds putative microRNA binding sites in the sequence of interest, then identifies the targeting microRNA.

::DEVELOPER

the Computational Medicine Center at the Sidney Kimmel Medical College of Thomas Jefferson University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • Java

:: DOWNLOAD

RNA 22

:: MORE INFORMATION

Citation:

Bioinformatics. 2012 Dec 15;28(24):3322-3. doi: 10.1093/bioinformatics/bts615. Epub 2012 Oct 16.
Interactive exploration of RNA22 microRNA target predictions.
Loher P1, Rigoutsos I.

SVMicrO 20100315 – Mammalian MicroRNA Target Prediction

SVMicrO 20100315

:: DESCRIPTION

SVMicrO is a 2-stage SVM based new miRNA target prediction algorithm. It assumes a 2-stage structure including a site support vector machine (SVM) followed by a UTR-SVM. SMVicrO makes prediction based on 21 optimal site features and 18 optimal UTR features, selected by training from a comprehensive collection of 113 site and 30 UTR features.

::DEVELOPER

SVMicrO team

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

 SVMicrO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2010 Sep 22;11:476. doi: 10.1186/1471-2105-11-476.
Improving performance of mammalian microRNA target prediction.
Liu H1, Yue D, Chen Y, Gao SJ, Huang Y.

TargetThermo – microRNA Target Prediction under relaxed seed and no conservation requirements

TargetThermo

:: DESCRIPTION

The TargetThermo package uses an energy-based linear regression model to compute predicted expression fold change of a gene caused by a miRNA.

::DEVELOPER

Uwe Ohler’s Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 TargetThermo

:: MORE INFORMATION

mEAT 1.0 – microRNA Enrichment Analysis Tool

mEAT 1.0

:: DESCRIPTION

mEAT is the microRNA Enrichment Analysis Tool

::DEVELOPER

Uwe Ohler’s Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 mEAT

:: MORE INFORMATION

Citation:

Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M Jr, Jungkamp AC, Munschauer M, Ulrich A, Wardle GS, Dewell S, Zavolan M, Tuschl T.
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
Cell 2010. 141(1):p129-141