X-LRT 1.0 – Estimate Genetic Risks and Test Association with X-linked Markers

X-LRT 1.0

:: DESCRIPTION

X-LRT is a suite of family-based tests for detecting association of X-chromosome genes. This is a likelihood-based approach which can perform hypothesis testing as well as estimation of disease-related marker relative risks under a case-parent design. This test uses nuclear family with a single affected proband and allows additional siblings and missing parental genotypes. This program can test both single marker and haplotypes association.

::DEVELOPER

Duke Molecular Physiology Institute

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 X-LRT

:: MORE INFORMATION

Citation

Zhang L, Martin ER, Chung RH, Li YJ, Morris RW. (2008)
X-LRT: a likelihood approach to estimate genetic risks and test association with X-linked markers using a case-parents design.
Genetic Epidemiology May;32(4):370-80.

PleioGRiP 0.02 – Genetic Risk Prediction with Pleiotropy

PleioGRiP 0.02

:: DESCRIPTION

PleioGRiP is a program  that performs a genome-wide Bayesian model search to identify SNPs associated with a discrete phenotype and uses SNPs ranked by Bayes factor to produce nested Bayesian classifiers.

::DEVELOPER

Stephen W. Hartley and Paola Sebastiani

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/ MacOsX
  • Java

:: DOWNLOAD

 PleioGRiP

:: MORE INFORMATION

Citation

PleioGRiP: genetic risk prediction with pleiotropy
Stephen W. Hartley and Paola Sebastiani
Bioinformatics (2013) 29 (8): 1086-1088.