PAINTOR 3.1 – Integration of Functional and Association data in Fine-mapping Studies

PAINTOR 3.1

:: DESCRIPTION

PAINTOR (Probabilistic Annotation INtegraTOR) is a probabilistic framework that integrates association strength with genomic functional annotation data to improve accuracy in selecting plausible causal variants for functional validation.

::DEVELOPER

Bogdan Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 PAINTOR

:: MORE INFORMATION

Citation:

Integrating functional data to prioritize causal variants in statistical fine-mapping studies.
Kichaev G, Yang WY, Lindstrom S, Hormozdiari F, Eskin E, Price AL, Kraft P,Pasaniuc B.
PLoS Genet. 2014 Oct 30;10(10):e1004722. doi: 10.1371/journal.pgen.1004722. eCollection 2014.

DHSMAP 2.0 / DHS-R – Fine-mapping of Qualitative Traits by use of Linkage Disequilibrium

DHSMAP 2.0

:: DESCRIPTION

DHSMAP (Decay of Haplotype Sharing MAPping Software) is a program that fine-maps qualitative traits by linkage disequilibrium.

::DEVELOPER

Andrew Strahs, Kenneth Wilder, Mary Sara McPeek

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows / MacOsX
  • C Compier

:: DOWNLOAD

 DHSMAP  , Paralleled DHSMAP , DHS-R (modified version of DHSMAP)

:: MORE INFORMATION

Citation

McPeek and Strahs (1999),
Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping,
American Journal of Human Genetics 65:858-875.

Zhang J., Schneider D., Ober C., McPeek M. S.
Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals
(2005) Genetic Epidemiology, vol. 29, pp. 128-140