DPPH – Perfect Phylogeny Haplotyping

DPPH

:: DESCRIPTION

DPPH (Perfect Phylogeny Haplotyper: a direct method )is a program for inferring haplotypes from genotypes to determine if there are resulting haplotypes that fit a tree model (i.e. a perfect phylogeny, a coalescent). In more population genetic terms, DPPH determines whether a set of SNP genotypes can be explained by haplotype pairs that could have evolved on a coalescent under the no-recombination, infinite sites model. Hence it determines for SNP genotype data what the three or four gametes test (depending on whether the tree is rooted or not) determines for haplotype data.

::DEVELOPER

Dan Gusfield’s group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/MacOsX

:: DOWNLOAD

   DPPH

:: MORE INFORMATION

Citation

Bafna V, Gusfield D, Lancia G, Yooseph S.
Haplotyping as Perfect Phylogeny: A Direct Approach
J Comput Biol. 2003;10(3-4):323-40.