MBMDR 4.4.1 – Model-Based Multifactor Dimensionality Reduction

MBMDR 4.4.1

:: DESCRIPTION

MBMDR (model-based multifactor dimensionality reduction) is a software that is able to detect multiple sets of significant gene-gene and/or gene-environment interactions in relation to a trait of interest, while efficiently controlling type I error rates. The trait can either be expressed on a binary scale, or on a continuous scale.

::DEVELOPER

the Statistical Genetics Research Club

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows with Cygwin

:: DOWNLOAD

 MBMDR

:: MORE INFORMATION

Citation

gammaMAXT: a fast multiple-testing correction algorithm.
Lishout FV, Gadaleta F, Moore JH, Wehenkel L, Steen KV.
BioData Min. 2015 Nov 20;8:36. doi: 10.1186/s13040-015-0069-x.

Bioinformatics. 2010 Sep 1;26(17):2198-9. Epub 2010 Jul 1.
mbmdr: an R package for exploring gene-gene interactions associated with binary or quantitative traits.
Calle ML, Urrea V, Malats N, Van Steen K.

FAM-MDR – Family-Based Multifactor Dimensionality Reduction

FAM-MDR

:: DESCRIPTION

FAM-MDR is a multifactor dimensionality reduction method for epistasis detection in small or extended pedigrees.

::DEVELOPER

the Statistical Genetics Research Club

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • R package

:: DOWNLOAD

 FAM-MDR

:: MORE INFORMATION

Citation

FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals.
Cattaert T, Urrea V, Naj AC, De Lobel L, De Wit V, Fu M, Mahachie John JM, Shen H, Calle ML, Ritchie MD, Edwards TL, Van Steen K.
PLoS One. 2010 Apr 22;5(4):e10304.