CoSBI – Identify Combinatorial Chromatin Modification Patterns across Genomic Loci

CoSBI

:: DESCRIPTION

CoSBI (Coherent and Shifted Bicluster Identification) is a scalable subspace clustering algorithm  to identify the complete set of combinatorial chromatin modification patterns across the entire genome.

::DEVELOPER

Tan Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 CoSBI

:: MORE INFORMATION

Citation:

Nucleic Acids Res. 2011 May;39(10):4063-75. doi: 10.1093/nar/gkr016. Epub 2011 Jan 25.
Combinatorial chromatin modification patterns in the human genome revealed by subspace clustering.
Ucar D1, Hu Q, Tan K.

ChAT – Unsupervised algorithm to Search Combinatorial Chromatin Signatures.

ChAT

:: DESCRIPTION

ChAT (Chromatin-profile Alignment followed by Tree-clustering algorithm) employs dynamic programming of combinatorial histone modification profiles to identify locally similar chromatin sub-regions and provides complementary utility with respect to existing methods.

::DEVELOPER

Jordan Lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux
  • R Program

:: DOWNLOAD

  ChAT

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2012 Nov;40(21):10642-56. doi: 10.1093/nar/gks848. Epub 2012 Sep 18.
Chromatin signature discovery via histone modification profile alignments.
Wang J, Lunyak VV, Jordan IK.