BPPH – Perfect Phylogeny Haplotyper

BPPH

:: DESCRIPTION

BPPH (Perfect Phylogeny Haplotyper: The Berkeley method ) is a program for inferring haplotypes from genotypes to determine if there are resulting haplotypes that fit a tree model (i.e. a perfect phylogeny, a coalescent). In more population genetic terms, BPPH determines whether a set of SNP genotypes can be explained by haplotype pairs that could have evolved on a coalescent under the no-recombination, infinite sites model. Hence it determines for SNP genotype data what the three or four gametes test (depending on whether the tree is rooted or not) determines for haplotype data.

::DEVELOPER

Dan Gusfield’s group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • MacOsX

:: DOWNLOAD

 BPPH

:: MORE INFORMATION

Citation

Haplotyping as Perfect Phylogeny: Conceptual Framework and Efficient Solutions
D. Gusfield In Proceedings of RECOMB, Sixth Annual Conference on Research in Computational Molecular Biology, April 2002