AntigenicTreeTools 1.0 – Infer Antigenic Trees to resolve the Antigenic Impact of Amino Acid Changes

AntigenicTreeTools 1.0

:: DESCRIPTION

AntigenicTreeTools infer antigenic trees to resolve the antigenic impact of amino acid changes mapped to individual branches of a phylogenetic tree. For sufficiently resolved branches, this allows to quantify the antigenic impact of single amino acid changes. However, the software is also applicable to problems where a phylogenetic tree and pair-wise phenotypic distances are available.

::DEVELOPER

Algorithmic Bioinformatics, Heinrich-Heine-Universität Düsseldorf

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Java

:: DOWNLOAD

 AntigenicTreeTools

:: MORE INFORMATION

Citation:

Steinbrück L, McHardy AC (2012)
Inference of Genotype–Phenotype Relationships in the Antigenic Evolution of Human Influenza A (H3N2) Viruses.
PLoS Comput Biol 8(4): e1002492. doi:10.1371/journal.pcbi.1002492