CAIcal 1.4 – Assess Codon Usage Adaptation

CAIcal 1.4

:: DESCRIPTION

The CAIcal (Codon Adaptation Index calulator) server performs several computations in relation to codon usage and the codon adaptation of DNA or RNA sequences to host organisms.

::DEVELOPER

P. Puigbo, Ph.D.

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux
  • Perl
  • TCL/TK

:: DOWNLOAD

  CAIcal

:: MORE INFORMATION

Citation

Puigbo P, Bravo IG and Garcia-Vallve S. (2008)
CAIcal: a combined set of tools to assess codon usage adaptation.
Biology Direct, 3:38.

JCat 1.0 – Java Codon Adaptation Tool

JCat 1.0

:: DESCRIPTION

JCat (Java Codon Adaptation Tool)presents a simple method to adapt the Codon Usage to most sequenced prokaryotic organisms and selected eukaryotic organisms. The codon adaptation plays a major role in cases where foreign genes are expressed in hosts and the codon usage of the host differs from that of the organism where the gene stems from. Unadapted codons in the host can for example lead to a minor expression rate.

::DEVELOPER

Andreas Grote

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Java

:: DOWNLOAD

 JCat

:: MORE INFORMATION

Citation

Grote A, Hiller K, Scheer M, Munch R, Nortemann B, Hempel DC, Jahn D.
JCat: a novel tool to adapt codon usage of a target gene to its potential expression host.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W526-31.