SMUG – Somatic Mutation Gleaner for Detecting Tumor Somatic Mutations

SMUG

:: DESCRIPTION

SMUG (Somatic Mutation Gleaner) was developed to effectively detect base substitutions and loss of heterozygosity (LOH) using next-generation sequencing data for normal and tumor tissues. It first screens bam files using walker programs (modules we developed to run under GATK), and then summarizes the results using Perl scripts.

Advertisement

::DEVELOPER

Chun Li, Ph.D.

:: REQUIREMENTS

:: DOWNLOAD

 SMUG

:: MORE INFORMATION

Citation

Song Z, Long J, He J, Shi J, Shu XO, Cai Q, Zheng W, Li C (2012)
Efficient detection of tumor somatic mutations using next-generation sequencing data.
(to be submitted)

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.