SAIGE 0.44.6.5

:: DESCRIPTION

SAIGE is an R-package for testing for associations between genetic variants and binary phenotypes with adjusting for sample relatedness and case-control imbalance.

::DEVELOPER

Lee lab for Statistical Genetics and Data Science

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux /  Windows / MacOsX
• R Package

:: MORE INFORMATION

Citation

Zhou W, Nielsen JB, Fritsche LG, Dey R, Gabrielsen ME, Wolford BN, LeFaive J, VandeHaar P, Gagliano SA, Gifford A, Bastarache LA, Wei WQ, Denny JC, Lin M, Hveem K, Kang HM, Abecasis GR, Willer CJ, Lee S.
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
Nat Genet. 2018 Sep;50(9):1335-1341. doi: 10.1038/s41588-018-0184-y. Epub 2018 Aug 13. PMID: 30104761; PMCID: PMC6119127.