RASER 2.0
:: DESCRIPTION
RASER is a likelihood based method for testing and detecting site-specific evolutionary rate shifts.
Given a multiple sequence alignment (MSA) and a phylogenetic tree, the program determines:
(a) Whether or not site-specific rate shifts characterize the evolution of a protein, and
(b) If so, points to the specific sites and lineages in which these shifts have most likely occurred.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux / Windows
:: DOWNLOAD
:: MORE INFORMATION
Citation
Penn O, Stern A, Rubinstein ND, Dutheil J, Bacharach E, Galtier N., Pupko T. 2008.
Evolutionary Modeling of Rate Shifts Reveals Specificity Determinants in HIV-1 Subtypes.
PLoS Computational Biology 4(11): e1000214.