quandico 1.14 – Quantitative Analysis of differences in Copy Numbers

quandico 1.14

:: DESCRIPTION

The tool quandico applies statistical methods to detect copy number variations (CNV) in a sample by comparing the read counts from next generation sequencing (NGS) performed after PCR-enrichment of regions of interest, typically a set of genes with known or expected relevance for the sample, e.g. genes that play a role in cancer. Counts from a normal control (ideally matched normal from the same individual, e.g. healthy tissue) are required.

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::DEVELOPER

Frank Reinecke

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • R
  • Perl

:: DOWNLOAD

 quandico

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2015 Jan 28;16(1):17.
Quantitative analysis of differences in copy numbers using read depth obtained from PCR-enriched samples and controls.
Reinecke F, Satya R, DiCarlo J.