OLego 1.1.7 – Senstive and fast Splice Mapping for mRNA-seq reads

OLego 1.1.7

:: DESCRIPTION

OLego is a program specifically designed for de novo spliced mapping of mRNA-seq reads. OLego adopts a seeding and extension scheme, and does not rely on a separate external mapper. It achieves high sensitivity of junction detection by using very small seeds (12-14 nt), efficiently mapped using Burrows-Wheeler transform (BWT) and FM-index. This also makes it particularly sensitive for discovering small exons. It is implemented in C++ with full support of multiple threading, to allow fast processing of large-scale data.

Advertisement

::DEVELOPER

Zhang Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 OLego

:: MORE INFORMATION

Citation

OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds.
Wu J, Anczuków O, Krainer AR, Zhang MQ, Zhang C.
Nucleic Acids Res. 2013 Apr 9.

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.