EditR 1.0.8 / MultiEditR 1.1.0 – Multiple Edit Deconvolution by Inference of Traces in R

EditR 1.0.8 / MultiEditR 1.1.0

:: DESCRIPTION

EditR is an algorithm for simple and cost effective measurement of base editing by quantifying Sanger trace fluorescence

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MultiEditR is an easy validation method for detecting and quantifying RNA editing from Sanger sequencing.

::DEVELOPER

Moriarity Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R

:: DOWNLOAD

EditR , MultiEditR

:: MORE INFORMATION

Citation

Kluesner MG, Nedveck DA, Lahr WS, Garbe JR, Abrahante JE, Webber BR, Moriarity BS.
EditR: A Method to Quantify Base Editing from Sanger Sequencing.
CRISPR J. 2018 Jun;1(3):239-250. doi: 10.1089/crispr.2018.0014. PMID: 31021262; PMCID: PMC6694769.

Kluesner MG, Tasakis RN, Lerner T, Arnold A, Wüst S, Binder M, Webber BR, Moriarity BS, Pecori R.
MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq.
Mol Ther Nucleic Acids. 2021 Jul 21;25:515-523. doi: 10.1016/j.omtn.2021.07.008. PMID: 34589274; PMCID: PMC8463291.

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