EditR 1.0.8 / MultiEditR 1.1.0

:: DESCRIPTION

EditR is an algorithm for simple and cost effective measurement of base editing by quantifying Sanger trace fluorescence

MultiEditR is an easy validation method for detecting and quantifying RNA editing from Sanger sequencing.

::DEVELOPER

Moriarity Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

EditR , MultiEditR

:: MORE INFORMATION

Citation

Kluesner MG, Nedveck DA, Lahr WS, Garbe JR, Abrahante JE, Webber BR, Moriarity BS.
EditR: A Method to Quantify Base Editing from Sanger Sequencing.
CRISPR J. 2018 Jun;1(3):239-250. doi: 10.1089/crispr.2018.0014. PMID: 31021262; PMCID: PMC6694769.

Kluesner MG, Tasakis RN, Lerner T, Arnold A, Wüst S, Binder M, Webber BR, Moriarity BS, Pecori R.
MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq.
Mol Ther Nucleic Acids. 2021 Jul 21;25:515-523. doi: 10.1016/j.omtn.2021.07.008. PMID: 34589274; PMCID: PMC8463291.

EditR 1.0.8 / MultiEditR 1.1.0 – Multiple Edit Deconvolution by Inference of Traces in R