Mechismo – Mechanistic Interpretations of Structural Modifications

Mechismo

:: DESCRIPTION

Mechismo is a tool that lets you find potential mechanisms for how proteins interact with other molecules and more importantly for how any mutations or post-translational modifications that might affect these interactions, and consequently an entire biological system.

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::DEVELOPER

Russell Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Betts MJ, Lu Q, Jiang YY, Drusko A, Wichmann A, Utz M, Valtierra-Gutiérrez IA, Schlesner M, Jaeger N, Jones Dt, Pfister S, Lichter P, Eils R, Siebert R, Bork B, Apic G, Gavin AC, Russell RB
Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions
Nucleic Acids Res. 2015 Jan;43(2):e10. doi: 10.1093/nar/gku1094.