LASSIE – Linear Allele-Specific Selection InferencE

LASSIE

:: DESCRIPTION

ASSIE is a statistical model for inferring selection coefficients associated with coding variants in the human genome.

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::DEVELOPER

Siepel Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • Python

:: DOWNLOAD

ASSIE

 :: MORE INFORMATION

Citation

Huang YF, Siepel A.
Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease.
Genome Res. 2019 Aug;29(8):1310-1321. doi: 10.1101/gr.245522.118. Epub 2019 Jun 27. PMID: 31249063; PMCID: PMC6673719.

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