HEGESMA 2.0
:: DESCRIPTION
HEGESMA (HEterogeneity and GEnome Search Meta Analysis)is a comprehensive software for performing genome scan meta-analysis, a quantitative method to identify genetic regions (bins) with consistently increased linkage score across multiple genome scans, and for testing the heterogeneity of the results of each bin across scans. The program provides as an output the average of ranks and three heterogeneity statistics, as well as corresponding significance levels. Statistical inferences are based on Monte Carlo permutation tests. The program allows both unweighted and weighted analysis, with the weights for each study as specified by the user. Furthermore, the program performs heterogeneity analyses restricted to the bins with similar average ranks.
::DEVELOPER
Department of Biomathematics. School of Medicine. University of Thessaly.
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Windows
:: DOWNLOAD
:: MORE INFORMATION
Citation
Elias Zintzaras1, and John P. A. Ioannidis
HEGESMA: genome search meta-analysis and heterogeneity testing
Bioinformatics,21 (18): 3672-3673.