GEMSTAT 1.5.0 – Thermodynamics-based Modeling of Gene Expression from Regulatory Sequences

GEMSTAT 1.5.0

:: DESCRIPTION

GEMSTAT  (Gene Expression Modeling based on Statistical Thermodynamics) is a thermodynamics-based model to predict gene expression driven by any DNA sequence, as a function of transcription factor concentrations and their DNA-binding specificities.

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::DEVELOPER

The Sinha Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / Mac OsX
  • C++ Compiler

:: DOWNLOAD

 GEMSTAT

:: MORE INFORMATION

Citation

Thermodynamics-based models of transcriptional regulation by enhancers: the roles of synergistic activation, cooperative binding and short-range repression.
He X, Samee MA, Blatti C, Sinha S.
PLoS Comput Biol. 2010 Sep 16;6(9). pii: e1000935. doi: 10.1371/journal.pcbi.1000935.