e-Driver
:: DESCRIPTION
e-Driver is a method that exploits the internal distribution of somatic missense mutations between the protein’s functional regions (domains or intrinsically disordered regions) to find those that show a bias in their mutation rate as compared with other regions of the same protein, providing evidence of positive selection and suggesting that these proteins may be actual cancer drivers.
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::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux / Windows/ MacOsX
- R
- Perl
:: DOWNLOAD
:: MORE INFORMATION
Citation:
Bioinformatics. 2014 Jul 26. pii: btu499.
e-Driver: a novel method to identify protein regions driving cancer.
Porta-Pardo E, Godzik A.