deFuse 0.8.2
:: DESCRIPTION
deFuse is a software package for gene fusion discovery using RNA-Seq data. The software uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. A classifier trained on real fusions and false positives is applied to the assembled sequences. The software produces a fully annotated output for each predicted fusion. The software is designed to be run out of the box with little configuration, and is compatible SGE, PBS and LSF compute clusters.
::DEVELOPER
Lab for Bioinformatics and Computational Genomics
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux
:: DOWNLOAD
:: MORE INFORMATION
Citation
McPherson A, Hormozdiari F, Zayed A, Giuliany R, Ha G, et al. (2011)
deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data
PLoS Comput Biol 7(5): e1001138. doi:10.1371/journal.pcbi.1001138