CRISPRO v1.0.2 – Analysis and Visualization of Saturating Mutagenesis CRISPR Screens

CRISPRO v1.0.2

:: DESCRIPTION

CRISPRO is a pipeline to process next generation sequnecing data from saturating mutagenesis CRISPR screens, whereby sgRNAs are mapped to amino acids of the protein, allowing for the inference of functional scores for amino acids in a protein.

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::DEVELOPER

bauer lab

:: SCREENSHOTS

N/a

:: REQUIREMENTS

  • Linux /  Windows
  • Python
  • R

:: DOWNLOAD

CRISPRO

:: MORE INFORMATION

Citation

Schoonenberg VAC, Cole MA, Yao Q, Macias-Treviño C, Sher F, Schupp PG, Canver MC, Maeda T, Pinello L, Bauer DE.
CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis.
Genome Biol. 2018 Oct 19;19(1):169. doi: 10.1186/s13059-018-1563-5. PMID: 30340514; PMCID: PMC6195731.

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