coloc 5.1.0 – Colocalisation Tests of Two Genetic Traits

coloc 5.1.0

:: DESCRIPTION

coloc takes p-values resulting from an association with a trait (a biomarker for example) and compares them with liver expression data outputting a posterior probability for a common signal within a region defined by the expression probe (200Kb upstream and downstream from the probe).

Advertisement

::DEVELOPER

Wallace group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • linux/ Windows/ MacOsX
  • R

:: DOWNLOAD

 coloc

:: MORE INFORMATION

Citation

Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.
Giambartolomei C, Vukcevic D, Schadt EE, Franke L, Hingorani AD, Wallace C, Plagnol V.
PLoS Genet. 2014 May 15;10(5):e1004383. doi: 10.1371/journal.pgen.1004383.