APEG – Affinity Prediction by Epigenome and Genome

APEG

:: DESCRIPTION

APEG uses a biophysical model to analyze transcription (TF)-DNA binding data, such as ChIP-seq data by incorporating epigenomic modifications and genome sequence data. This model can learn synergistic and antagonistic interactions between specific TFs and epigenomic modifications from genome-wide TF binding and epigenomic data.

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::DEVELOPER

Zhong Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

APEG

:: MORE INFORMATION

Citation

PLoS Comput Biol. 2013;9(12):e1003367. doi: 10.1371/journal.pcbi.1003367.
Understanding variation in transcription factor binding by modeling transcription factor genome-epigenome interactions.
Chen CC, Xiao S, Xie D, Cao X, Song CX, Wang T, He C, Zhong S.

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