Antigen Explorer – Antigen Combinations for Precision Cancer Recognition

Antigen Explorer

:: DESCRIPTION

Antigen Explorer is an interactive resource for browsing antigen combinations for more precise tumor recognition. Leveraging expression data from TCGA and GTEx, the discrimination potential of all possible combinations of surface antigens were scored for 33 tumor types. Users can explore the top predictions and make interactive plots to evaluate an antigen pair against normal tissue cross-reactivity.

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::DEVELOPER

Troyanskaya Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Dannenfelser R, Allen GM, VanderSluis B, Koegel AK, Levinson S, Stark SR, Yao V, Tadych A, Troyanskaya OG, Lim WA.
Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies.
Cell Syst. 2020 Sep 23;11(3):215-228.e5. doi: 10.1016/j.cels.2020.08.002. Epub 2020 Sep 10. PMID: 32916097; PMCID: PMC7814417.

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