JET
:: DESCRIPTION
JET (Joint Evolutionary Trees) is a method designed to detect very different types of interactions of a protein with another protein, ligands, DNA, and RNA. It uses carefully designed sampling method, making sequence analysis more sensitive to the functional and structural importance of individual residues, and a clustering method parametrized on the target structure for the detection of patches on protein surfaces and their extension into predicted interaction sites.
::DEVELOPER
Laboratory of Computational and Quantitative Biology(LCQB)
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux / MacOsX
- Java
- ClustalW
- Naccess
- PSI-BLAST from BLAST Toolkit
:: DOWNLOAD
:: MORE INFORMATION
Citation
Engelen S, Trojan LA, Sacquin-Mora S, Lavery R, Carbone A.
Joint evolutionary trees: a large-scale method to predict protein interfaces based on sequence sampling,
PLoS Comput Biol, 5(1):e1000267, 2009.