rSW-seq
:: DESCRIPTION
rSW-seq is designed to identify copy number alterations between tumor-vs-matched normal genomes (or between normal-vs-normal genomes for CNV detection) from deep sequencing data generated by next-generation sequencing. Compared to other algorithms (BreakDancer or MoDIL) using PEM (paired-end mapping) signatures, rSW-seq uses ‘read-depth’ as primary measure, which can be applied to single-end sequencing read set.
::DEVELOPER
Tae-Min Kim. , Peter Park’s lab at CBMI, Harvard Medical School
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux / MacOsX / Windows
:: DOWNLOAD
:: MORE INFORMATION
Citation
BMC Bioinformatics. 2010 Aug 18;11:432.
rSW-seq: algorithm for detection of copy number alterations in deep sequencing data.
Kim TM, Luquette LJ, Xi R, Park PJ.