Facet v1.4 – Multiple Alignment Accuracy Estimation and Parameter Advising

Facet v1.4

:: DESCRIPTION

Facet (Feature-based accuracy estimator) computes a single estimate of accuracy as a linear combination of efficiently-computable feature functions.

::DEVELOPER

Dr. Dan DeBlasio

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOs

:: DOWNLOAD

Facet

:: MORE INFORMATION

Citation

J Comput Biol. 2013 Apr;20(4):259-79. doi: 10.1089/cmb.2013.0007. Epub 2013 Mar 14.
Accuracy estimation and parameter advising for protein multiple sequence alignment.
Kececioglu J, DeBlasio D.

STEM 2.0 / STEM-hy 1.0 – Species Tree Estimation using Maximum likelihood (with hybridization)

STEM 2.0 / STEM-hy 1.0

:: DESCRIPTION

STEM-hy is a program for inferring maximum likelihood species trees from a collection of estimated gene trees under the coalescent model

::DEVELOPER

Laura S. Kubatko

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/ MacOsX
  • Java

:: DOWNLOAD

 STEM / STEM-hy

:: MORE INFORMATION

Citation

Kubatko, L., B. C. Carstens, and L. L. Knowles. 2009.
STEM: Species Tree Estimation using Maximum likelihood for gene trees under coalescence,
Bioinformatics (2009) 25 (7): 971-973.doi: 10.1093/bioinformatics/btp079

BEESEM – Binding Energy Estimation on SELEX with Expectation Maximization

BEESEM

:: DESCRIPTION

The BEESEM program is designed for transcription factor binding motif discovery using HT-SELEX data.

::DEVELOPER

Stormo Lab in Department of Genetics, Washington University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

BEESEM

:: MORE INFORMATION

Citation

Bioinformatics. 2017 Aug 1;33(15):2288-2295. doi: 10.1093/bioinformatics/btx191.
BEESEM: estimation of binding energy models using HT-SELEX data.
Ruan S, Swamidass SJ, Stormo GD

TM 20110802 – Multiple Trait Estimation of Variance Components

TM 20110802

:: DESCRIPTION

TM (Threshold Model) is a (Fortran90) software for multiple trait estimation of variance components, breeding values and fixed effects in threshold, linear and censored linear models in animal breeding.  As of August, 2011 it has been modified to accept random seeds on input, and also to include user-defined covariance matrices among individuals (for instance, genomic relationship matrices).

::DEVELOPER

Andrés Legarra , andres dot legarra at toulouse point inra punto fr

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux
  • Fortran90

:: DOWNLOAD

 TM

:: MORE INFORMATION

PMLE 2.0 – Maximum Likelihood Estimation of Migration Rates for Wright Island Model

PMLE 2.0

:: DESCRIPTION

PMLE estimates the gene flow parameter q for a collection of two or more semi-isolated populations by (pseudo) maximum likelihood using either single or multi locus, haploid or diploid, genotype data. Suitable molecular data types minimally include allozymes, microsatellites, and RFLPs.

::DEVELOPER

Rannala Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows

:: DOWNLOAD

 PMLE

:: MORE INFORMATION

Citation

Rannala, B., and J. A. Hartigan. 1996.
Estimating gene flow in island populations.
Genetical Research 67:147-158

BACTFREQ – Maximum Likelihood Estimation of Bacterial Allele Frequencies

BACTFREQ

:: DESCRIPTION

BACTFREQ estimates allele frequencies and perform the Monte Carlo simulations (replaces BFREQ program)

::DEVELOPER

Rannala Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ MacOsX / Windows
  • C Compiler

:: DOWNLOAD

  BACTFREQ

:: MORE INFORMATION

Citation

E. C. Anderson and P. A. Scheet. 2001.
Improving the estimation of bacterial allele frequencies.
Genetics 158:1383-1386.

B. Rannala, W. Qui, and D. E. Dykhuizen. 2000.
Methods for estimating gene frequencies and detecting selection in bacterial populations
Genetics 155: 499-508.

pim 0.3 – Alignment-free Estimation of Genetic Diversity

pim 0.3

:: DESCRIPTION

pim is a program for efficiently estimating the number of mismatches between a pair of unaligned sequences

::DEVELOPER

Bernhard Haubold

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/MacOsX
  • C Compiler

:: DOWNLOAD

 pim

:: MORE INFORMATION

Citation

B. Haubold, F. A. Reed, and P. Pfaffelhuber.
Alignment-free estimation of nucleotide diversity.
Bioinformatics, doi: 10.1093/bioinformatics/btq689, 2010.

CHROMIBD 1.1 – Estimation of Identity-by-Descent Probabilities between Haplotypes and Genotyped Ancestors

CHROMIBD 1.1

:: DESCRIPTION

CHROMIBD computes IBD probabilities between a “target chromosome” and a set of “parental chromosomes” (the method works best without “phantom parental chromosomes”). These chromosomes need to be phased and the program relies only on phased (non-missing) markers in target and parental chromosomes. The program works only with bi-allelic markers such as SNPs.

::DEVELOPER

Unit of Animal Genomics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 CHROMIBD

:: MORE INFORMATION

Citation

T. Druet and F. Farnir (2011)
Modeling of identity-bydescent processes along a chromosome between haplotypes and their genotyped ancestors.
Genetics. 2011 June; 188(2): 409–419.

PSCN 1.0 – Parent-Specific Copy Number Estimation

PSCN 1.0

:: DESCRIPTION

PSCN segments the genome of a sample into homogeneous parts and gives an estimation of parent-specific DNA copy number using high-density SNP array data (logR and B-allele frequency). This package can be applied on platforms having both SNP probes and copy number probes.

::DEVELOPER

Hao Chen

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/Windows/MacOsX
  • R Package

:: DOWNLOAD

  PSCN

:: MORE INFORMATION

Citation

Chen, H., Xing, H. and Zhang, N.R., 2011,
Stochastic segmentation models for allele-specific copy number estimation with SNP-array data,
PLoS Computational Biology, 7, e1001060.

BN-BS – Estimation of Synonymous and Nonsynonymous Branch Lengths from Pairwise Distances

BN-BS

:: DESCRIPTION

BN-BS is a software to estimate branch lengths in terms of synonymous and nonsynonymous substitutions per site, while the tree topology is given. The program uses the modified Nei-Gojobori method (Zhang et al. 1998) to estimate pairwise synonymous and nonsynonymous distances among present-sequences and then estimates branch lengths and their variances by using the ordinary least-squares method.

::DEVELOPER

Jianzhi Zhang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 BN-BS

:: MORE INFORMATION

Citation:

Zhang J., H. F. Rosenberg, and M. Nei (1998)
Positive Darwinian selection after gene duplication in primate ribonuclease genes.
Proc. Natl. Acad. Sci. USA 95:3708-3713.