EpiPred – B-cell Epitope Prediction

EpiPred

:: DESCRIPTION

EpiPred is a software of B-cell epitope prediction and antibody-antigen docking

::DEVELOPER

Oxford Protein Informatics Group (OPIG)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • JRE
  • Python

:: DOWNLOAD

 EpiPred

:: MORE INFORMATION

Citation:

Improving B-cell epitope prediction and its application to global antibody-antigen docking.
Krawczyk K, Liu X, Baker T, Shi J, Deane CM.
Bioinformatics. 2014 Aug 15;30(16):2288-94. doi: 10.1093/bioinformatics/btu190.

CTLPred – SVM & ANN Based CTL epitope Prediction method

CTLPred

:: DESCRIPTION

CTLPred is a direct method for prediction of CTL epitopes crucial in subunit vaccine design.In direct methods the information or patterns of T cell epitopes instead of MHC binders were used for the development o f methods. The methods is based on elegant machine learning techniques like a Artificial Neural network and support vector machine .

::DEVELOPER

CTLPred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Bhasin,M. and Raghava, G.P.S. (2004)
Prediction of CTL epitopes using QM, SVM and ANN techniques.
Vaccine,22,3195-3201.

ABCpred – Artificial Neural Network based B-cell Epitope Prediction Server

ABCpred

:: DESCRIPTION

ABCpred server is to predict linear B cell epitope regions in an antigen sequence, using artificial neural network. This server will assist in locating epitope regions that are useful in selecting synthetic vaccine candidates, disease diagonosis and also in allergy research.

::DEVELOPER

ABCpred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Saha, S and Raghava G.P.S. (2006)
Prediction of Continuous B-cell Epitopes in an Antigen Using Recurrent Neural Network.
Proteins,65(1),40-48

BcePred – Predict B cell Epitope based on Physio-chemical Properties of Amino Acids

BcePred

:: DESCRIPTION

The BcePred server predicts B cell epitope based on physio-chemical properties of amino acids.

::DEVELOPER

BcePred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Saha.S and Raghava G.P.S.
BcePred:Prediction of Continuous B-Cell Epitopes in Antigenic Sequences Using Physico-chemical Properties.
In G.Nicosia, V.Cutello, P.J. Bentley and J.Timis (Eds.) ICARIS 2004, LNCS 3239, 197-204, Springer,2004.

CBTOPE – Conformational B-cell Epitope Prediction

CBTOPE

:: DESCRIPTION

CBTOPE server discriminate the antibody epitope residues and non-epitope residues for a given protein sequence.

::DEVELOPER

CBTOPE team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 CBTOPE

:: MORE INFORMATION

Citation

Immunome Res. 2010 Oct 20;6:6. doi: 10.1186/1745-7580-6-6.
Identification of conformational B-cell Epitopes in an antigen from its primary sequence.
Ansari HR1, Raghava GP.

IFNepitope – Predicting and Designing Interferon-gamma inducing Epitopes

IFNepitope

:: DESCRIPTION

IFNepitope is a web server to predict and design the epitope, which could induce the release of interferon gamma. The webserver has been developed on the basis of a dataset, which comprises of IFN-gamma inducing and non-inducing MHC class II binders.

::DEVELOPER

IFNepitope team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Biol Direct. 2013 Dec 5;8:30. doi: 10.1186/1745-6150-8-30.
Designing of interferon-gamma inducing MHC class-II binders.
Dhanda SK1, Vir P, Raghava GP.

BJTEpitope – T-cell Epitope Prediction for the MHC class I allele HLA-A*0201

BJTEpitope

:: DESCRIPTION

BJTEpitope is a software for T-cell epitope prediction for the MHC class I allele HLA-A*0201

::DEVELOPER

Center of Computational Biology, Beijing Institute of Basic Medical Sciences

:: SCREENSHOTS

BJTEpitope

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

  BJTEpitope

:: MORE INFORMATION

PREDIVAC – CD4+ T-cell Epitope Prediction for Vaccine Design

PREDIVAC

:: DESCRIPTION

Predivac implements a method for prediction of CD4+ T-cell epitopes based on the specificity-determining residues (SDRs) approach. SDRs are small set of structurally conserved amino acids in the peptide:protein interaction interface that are responsable for specific recognition events.

::DEVELOPER

Kobe Lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Web Browser

:: DOWNLOAD

   NO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2013 Feb 14;14(1):52. [Epub ahead of print]
PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity.
Oyarzún P, Ellis JJ, Bodén M, Kobe BT.

FRED 1.0 – Framework for T-cell Epitope Detection

FRED 1.0

:: DESCRIPTION

FRED is a framework for T-cell epitope detection that offers consistent, easy, and simultaneous access to well established prediction methods for MHC binding and antigen processing. FRED can handle polymorphic proteins and offers analysis tools to combine, benchmark, or compare different methods. It is implemented in Python in a modular way and can easily be extended by user defined methods.

DEVELOPER

the Kohlbacher lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows with cygwin / MacOsX
  • Python

:: DOWNLOAD

 FRED

:: MORE INFORMATION

Citation:

Feldhahn, M, Dönnes, P, Thiel, P, and Kohlbacher, O (2009).
FRED – A Framework for T-cell Epitope Detection
Bioinformatics, 25(20):2758-9.