PyInteraph 1.0 – Analysis of Interaction Networks in Structural Ensembles of Proteins

PyInteraph 1.0

:: DESCRIPTION

The PyInteraph software suite is a package designed to analyze intra- or inter-molecular interactions in structural ensembles derived both from molecular simulations or experiments (i.e. NMR-based structural ensembles)

::DEVELOPER

PyInteraph team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux
Python

:: DOWNLOAD

PyInteraph

:: MORE INFORMATION

Citation

J Chem Inf Model. 2014 Apr 17. [Epub ahead of print]
PyInteraph: A Framework for the Analysis of Interaction Networks in Structural Ensembles of Proteins.
Tiberti M1, Invernizzi G, Lambrughi M, Inbar Y, Schreiber G, Papaleo E.

SNPfold 1.01 – Identify RiboSNitches by leveraging GWAS data and an Analysis of the mRNA Structural Ensemble

SNPfold 1.01

:: DESCRIPTION

SNPfold evaluates the effects of SNPs (Single Nucleotide Polymorphisms) on the ensemble structure of an RNA. It takes as input an RNA sequence and one or more SNPs, and then evaluates the structural consequences of the mutation by computing a WT/SNP correlation coefficient. The smaller the correlation the larger the structural effects of the SNP.

::DEVELOPER

The Laederach Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Windows / Linux / Mac OsX
Python

:: DOWNLOAD

SNPfold

:: MORE INFORMATION

Citation

PLoS Genet. 2010 Aug 19;6(8):e1001074. doi: 10.1371/journal.pgen.1001074.
Disease-associated mutations that alter the RNA structural ensemble.
Halvorsen M, Martin JS, Broadaway S, Laederach A.

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