:: DESCRIPTION
PurBayes is an MCMC-based algorithm that uses next-generation sequencing data to estimate tumor purity and clonality for paired tumor-normal data.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
Bioinformatics. 2013 Aug 1;29(15):1888-9. doi: 10.1093/bioinformatics/btt293. Epub 2013 Jun 6.
PurBayes: estimating tumor cellularity and subclonality in next-generation sequencing data.
Larson NB1, Fridley BL.
:: DESCRIPTION
CITUP is a bioinformatics tool that can be used to infer tumor heterogeneity using multiple samples from a single patient. Given mutational frequencies for each sample, CITUP uses an optimization based algorithm to find the evolutionary tree best explaining the data.
::DEVELOPER
Lab for Bioinformatics and Computational Genomics
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
:: MORE INFORMATION
Citation
Clonality Inference in Multiple Tumor Samples using Phylogeny.
Malikic S, McPherson AW, Donmez N, Sahinalp CS.
Bioinformatics. 2015 Jan 6. pii: btv003.
:: DESCRIPTION
CLONET is a collection of R scripts which upon estimation of tumor admixture and ploidy infers the clonal hierarchy of genomic aberrations.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
:: DOWNLOAD
:: MORE INFORMATION
Citation:
Genome Biol. 2014 Aug 26;15(8):439. doi: 10.1186/s13059-014-0439-6.
Unraveling the clonal hierarchy of somatic genomic aberrations.
Prandi D, Baca SC, Romanel A, Barbieri CE, Mosquera JM, Fontugne J, Beltran H, Sboner A, Garraway LA, Rubin MA, Demichelis F.
