Baescs 2.0 – Estimate Calibration Curves and unknown Concentrations in Immunoassays

Baescs 2.0

:: DESCRIPTION

Baescs is a Bayesian approach to estimate calibration curves and unknown concentrations in immunoassays.

::DEVELOPER

The Center for Computational Immunology 

:: SCREENSHOTS

Baescs

::REQUIREMENTS

  • Linux/Windows

:: DOWNLOAD

 Baescs

:: MORE INFORMATION

Citation

Feng Feng; Ana Paula Sales; Thomas B. Kepler :
A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays.
Bioinformatics (2011) 27 (5): 707-712.

DatasetAssess – Estimate Error Rates in High-throughput Protein Interaction datasets

DatasetAssess

:: DESCRIPTION

 DatasetAssess is a tool to estimate error rates in high-throughput protein interaction datasets and other functional genomic data.

::DEVELOPER

Andreas Wagner Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 DatasetAssess

:: MORE INFORMATION

Citation:

Gilchrist, M.A., Salter, L.A., Wagner, A. (2004)
A statistical framework for combining and interpreting proteomic datasets.
Bioinformatics 20, 689-700

RVsharing 1.7.0 – Computes Estimates of the Probability of Related Individuals Sharing a Rare Variant

RVsharing 1.7.0

:: DESCRIPTION

RVsharing computes the probability that a rare variant is shared by related subjects, given that the variant was observed in any of them.

::DEVELOPER

Alexandre Bureau

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ WIndows/ MacOsX
  • R

:: DOWNLOAD

 RVsharing

:: MORE INFORMATION

Citation

Inferring rare disease risk variants based on exact probabilities of sharing by multiple affected relatives.
Bureau A, Younkin SG, Parker MM, Bailey-Wilson JE, Marazita ML, Murray JC, Mangold E, Albacha-Hejazi H, Beaty TH, Ruczinski I.
Bioinformatics. 2014 Apr 16. pii: btu198.

Coancestry 1.0.1.2 – Simulate, Estimate and Analyse Relatedness and Inbreeding Coefficients

Coancestry 1.0.1.2

:: DESCRIPTION

COANCESTRY is a computer program that implements 7 methods to estimate the pairwise relatedness between individuals and 4 methods to estimate individual inbreeding coefficients, using individual genotypes at a set of marker loci.

:: DEVELOPER

Dr Jinliang Wang

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 Coancestry

:: MORE INFORMATION

Citation

COANCESTRY: a program for simulating, estimating and analysing relatedness and inbreeding coefficients.
Wang J.
Mol Ecol Resour. 2011 Jan;11(1):141-5. doi: 10.1111/j.1755-0998.2010.02885.x.

AgeStructure 1.0 – Estimate Effective Size & Generation Interval of Population with overlapping Generations

AgeStructure 1.0

:: DESCRIPTION

AgeStructure is a computer program for estimating the generation interval, effective size, variances and covariances of lifetime number of offspring of an age structured population with overlapping generations.

:: DEVELOPER

Dr Jinliang Wang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOsX / Linux
  • Fortran 90/95 compiler

:: DOWNLOAD

 AgeStructure

:: MORE INFORMATION

Citation

Wang, J., Brekke, P. , Huchard, E., Knapp, L. A. , Cowlishaw, G. 2010.
Estimation of parameters of inbreeding and genetic drift in populations with overlapping generations.
Evolution, 64, 1704–1718.

Mash v2.3 – Fast Similarity Estimates via MinHash

Mash v2.3

:: DESCRIPTION

Mash is a software of fast genome and metagenome distance estimation using MinHash

::DEVELOPER

Treangen Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX

:: DOWNLOAD

Mash

:: MORE INFORMATION

Citation:

Genome Biol, 17 (1), 132
Mash: Fast Genome and Metagenome Distance Estimation Using MinHash
Brian D Ondov , Todd J Treangen , Páll Melsted , Adam B Mallonee , Nicholas H Bergman , Sergey Koren , Adam M Phillippy

mlRho 2.9 – Estimate the Population Mutation and Recombination Rates from Shotgun-Sequenced Diploid Genomes

mlRho 2.9

:: DESCRIPTION

mlRho takes as input a file with assembled reads from a single diploid individual and returns maximum likelihood estimates of the population mutation rate, , the sequencing error , the zygosity correlation, and the population recombination rate, 

::DEVELOPER

Bernhard Haubold

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ MacOsX
  • C Compiler

:: DOWNLOAD

 mlRho

:: MORE INFORMATION

Citation

B. Haubold, P. Pfaffelhuber, and M. Lynch.
mlRho: A program for estimating the population mutation and recombination rates from shotgun-sequenced diploid genomes.
Molecular Ecology, 19:277-284, 2010.

iAdmix 1.0 – Using population allele frequencies for Computing Individual Admixture Estimates

iAdmix 1.0

:: DESCRIPTION

iAdmix is a program to estimate individual admixture proportions from DNA sequencing experiments (exome sequencing, targeted sequencing, low coverage whole-genome sequencing or genotyping)

::DEVELOPER

Bansal Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows
  • Python

:: DOWNLOAD

 iAdmix

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2015 Jan 16;16(1):4.
Fast individual ancestry inference from DNA sequence data leveraging allele frequencies for multiple populations.
Bansal V, Libiger O.

Adapt-A-Rate 1.0 – Estimate the Rate of Adaptive Fixation in Population

Adapt-A-Rate 1.0

:: DESCRIPTION

Adapt-A-Rate is a program to estimate the rate of adaptive fixation in a population from sequences sampled at different points in time.

::DEVELOPER

Samir Bhatt and Oliver Pybus

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Linux / MacOSX
  • Java

:: DOWNLOAD

 Adapt-A-Rate

:: MORE INFORMATION

Citation:

Bhatt S, Holmes EC, Pybus OG (2011)
The genomic rate of molecular adaptation of the human influenza A virus.
Molecular Biology & Evolution In press

CoNe 1.01 – Estimate Ne from two temporal samples

CoNe 1.01

:: DESCRIPTION

CoNe computes the likelihood of Ne given data on two temporally spaced genetic samples. The statistical model used is based on the coalescent of the gene copies drawn in the second sample, as described in Berthier et al. (Genetics 2003, 160:741-51). The Monte Carlo computations to compute the likelihood, however, were developed by Eric Anderson, and are orders of magnitude faster than previous implementations.

::DEVELOPER

Eric C. Anderson

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOsX

:: DOWNLOAD

CoNe

:: MORE INFORMATION

Citation

Anderson, E. C.2005.
An efficient Monte Carlo method for estimating Ne from temporally spaced samples using a coalescent-based likelihood.
Genetics 170(2):955-967.

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