SANS / SANSparallel 2.3 – Interactive Homology Search against Uniprot

SANS / SANSparallel 2.3

:: DESCRIPTION

SANS is a program for searching protein sequence databases. It is as sensitive as BLAST when sequence identity is 50-100 %. SANS is faster than BLAST in batch mode. For example, a bacterial genome can be compared to Uniprot in one hour compared to 100 hours by BLAST.

SANSparallel takes a protein sequence as input and returns a set of similar sequences from Uniprot databases.

::DEVELOPER

Liisa Holm’s Bioinformatics Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 SANSparallel

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Sep 15;28(18):i438-i443. doi: 10.1093/bioinformatics/bts417.
SANS: high-throughput retrieval of protein sequences allowing 50% mismatches.
Koskinen JP1, Holm L.

Nucleic Acids Res. 2015 Apr 8. pii: gkv317.
SANSparallel: interactive homology search against Uniprot.
Somervuo P, Holm L.

CUDASW++ 3.1.2 – Parallel Smith Waterman Protein database search algorithm

CUDASW++ 3.1.2

:: DESCRIPTION

CUDASW++ (compute unified device architecture) is a bioinformatics software for Smith-Waterman protein database searches that takes advantage of the massively parallel CUDA architecture of NVIDIA Tesla GPUs to perform sequence searches 10x-50x faster than NCBI BLAST.

::DEVELOPER

Liu, Yongchao

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • CUDA toolkits and SDK 2.0 or higher.

:: DOWNLOAD

 CUDASW++

:: MORE INFORMATION

Citation:

Yongchao Liu, Bertil Schmidt, Douglas L. Maskell:
CUDASW++2.0: enhanced Smith-Waterman protein database search on CUDA-enabled GPUs based on SIMT and virtualized SIMD abstractions“.
BMC Research Notes, 2010, 3:93

Trnascan-SE 2.0.8 – Search for tRNA Genes in Genomic Sequence

Trnascan-SE 2.0.8

:: DESCRIPTION

tRNAscan-SE is a program for improved detection of transfer RNA genes in genomic sequence.

::DEVELOPER

the Lowe Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 Trnascan-SE

:: MORE INFORMATION

Citation:

tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes.
Lowe TM, Chan PP.
Nucleic Acids Res. 2016 May 12. pii: gkw413.

Lowe, T.M. and Eddy, S.R. (1997)
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.
Nucleic Acids Research, 25, 955-964.

PLAN 1.0 RC19 – High-throughput BLAST Searches and Managing and Mining Results

PLAN 1.0 RC19

:: DESCRIPTION

PLAN (Personal BLAST Navigator) is a versatile web platform that helps users to carry out various personalized pre- and post-BLAST tasks, including: (1) query and target sequence database management, (2) automated high-throughput BLAST searching, (3) indexing and searching of results, (4) filtering results online, (5) managing results of personal interest in favorite categories, (6) automated sequence annotation (such as NCBI NR and ontology-based annotation). PLAN integrates, by default, the Decypher hardware-based BLAST solution provided by Active Motif Inc. with a greatly improved efficiency over conventional BLAST software. BLAST results are visualized by spreadsheets and graphs and are full-text searchable. BLAST results and sequence annotations can be exported, in part or in full, in various formats including Microsoft Excel and FASTA. Sequences and BLAST results are organized in projects, the data publication levels of which are controlled by the registered project owners. In addition, all analytical functions are provided to public users without registration.

::DEVELOPER

The Zhao Bioinformatics Laboratory

:: REQUIREMENTS

:: DOWNLOAD

 PLAN

:: MORE INFORMATION

Citation:

He, J., Dai, X. and Zhao, X. (2007).
PLAN: A web platform for automating high-throughput BLAST searches and for managing and mining results.
BMC Bioninformatics 8:53.

3D-BLAST beta 1.02 – Protein Structure Search

3D-BLAST beta 1.02

:: DESCRIPTION

3D-BLAST is a very fast and accurate method for discovering the homologous proteins and evolutionary classifications of a newly determined protein structure.

::DEVELOPER

BioXGEM Lab.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/MacOsX

:: DOWNLOAD

 3D-BLAST

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2006 Aug 2;34(13):3646-59.
Protein structure database search and evolutionary classification.
Yang JM, Tung CH.

Genome Biol. 2007;8(3):R31.
Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database.
Tung CH, Huang JW, Yang JM.

YEASTRACT / YEASTRACT-DISCOVERER – Yeast Search for Transcriptional Regulators And Consensus Tracking

YEASTRACT / YEASTRACT-DISCOVERER

:: DESCRIPTION

YEASTRACT is a curated repository of more than 206000 regulatory associations between transcription factors (TF) and target genes in Saccharomyces cerevisiae, based on more than 1300 bibliographic references.

YEASTRACT-DISCOVERER is a set of tools that can be used to identify complex motifs found to be over-represented in the promoter regions of co-regulated genes.

::DEVELOPER

YEASTRACT team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

The YEASTRACT database: an upgraded information system for the analysis of gene and genomic transcription regulation in Saccharomyces cerevisiae.
Teixeira MC, Monteiro PT, Guerreiro JF, Gonçalves JP, Mira NP, Dos Santos SC, Cabrito TR, Palma M, Costa C, Francisco AP, Madeira SC, Oliveira AL, Freitas AT, Sá-Correia I.
Nucl. Acids Res. (2013)doi: 10.1093/nar/gkt1015

YEASTRACT: providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface.
Abdulrehman D, Monteiro PT, Teixeira MC, Mira NP, Lourenço AB, dos Santos SC, Cabrito TR, Francisco AP, Madeira SC, Aires RS, Oliveira AL, Sá-Correia I, Freitas AT.
Nucleic Acids Res. 2011 Jan;39(Database issue):D136-40. doi: 10.1093/nar/gkq964.

YEASTRACT-DISCOVERER: new tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae.
Monteiro PT, Mendes ND, Teixeira MC, d’Orey S, Tenreiro S, Mira NP, Pais H, Francisco AP, Carvalho AM, Louren?o AB, Sá-Correia I, Oliveira AL, Freitas AT.
Nucleic Acids Res. 2008 Jan;36(Database issue):D132-6.

The YEASTRACT database: a tool for the analysis of transcription regulatory associations in Saccharomyces cerevisiae.
Teixeira MC, Monteiro P, Jain P, Tenreiro S, Fernandes AR, Mira NP, Alenquer M, Freitas AT, Oliveira AL, Sá-Correia I.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D446-51.

Crossfinder 20150212 – Search for Protein Crosslinks formed by Site-specifically Incorporated Crosslinkers

Crossfinder 20150212

:: DESCRIPTION

Crossfinder automates the search for crosslinks formed by site-specifically incorporated crosslinking amino acids in LC-MS-MS data.

::DEVELOPER

Müller-Planitz Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 Crossfinder

:: MORE INFORMATION

Citation

Bioinformatics. 2015 Feb 11. pii: btv083.
Crossfinder-assisted mapping of protein crosslinks formed by site-specifically incorporated crosslinkers.
Mueller-Planitz F

iSARST / SARST / CPSARST – Rapid Protein Structural Similarity Searches

iSARST / SARST / CPSARST

:: DESCRIPTION

iSARST is a web server for efficient protein structural similarity searches.

CPSARST (Circular Permutation Search Aided by Ramachandran Sequential Transformation) is an efficient database search tool.

::DEVELOPER

10Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux

:: DOWNLOAD

 SARST / CPSARST 

:: MORE INFORMATION

Citation

Lo WC, Lee CY, Lee CC, Lyu PC:
iSARST: an integrated SARST web server for rapid protein structural similarity searches.
Nucleic Acids Research 2009, 37(Web Server issue):W545-W551; doi:10.1093/nar/gkp291.

Genome Biol. 2008 Jan 18;9(1):R11. doi: 10.1186/gb-2008-9-1-r11.
CPSARST: an efficient circular permutation search tool applied to the detection of novel protein structural relationships.
Lo WC1, Lyu PC.

MSPLIT 1.0 – Multiplexed Spectral Library Search

MSPLIT 1.0

:: DESCRIPTION

M-SPLIT is a spectral-library search tool for identification of mixture spectra of up to two peptides.

::DEVELOPER

CCMS The Center for Computational Mass Spectrometry

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/ MacOsX
  • Java

:: DOWNLOAD

 MSPLIT

:: MORE INFORMATION

Citation

Mol Cell Proteomics. 2010 Jul;9(7):1476-85. doi: 10.1074/mcp.M000136-MCP201. Epub 2010 Mar 27.
Peptide identification from mixture tandem mass spectra.
Wang J1, Pérez-Santiago J, Katz JE, Mallick P, Bandeira N.

PANOW 1.0 – Search of Rare Words in Biological Sequences

PANOW 1.0

:: DESCRIPTION

PANOW (Poisson Approximation for the Number of Occurrences of Words)is a software dedicated to the search of rare words in biological sequences (over- or under-represented words in DNA or protein sequences).

::DEVELOPER

Nicolas Vergne (vergne@genopole.cnrs.fr)@ Laboratoire de Mathématiques et Modélisation d’Évry

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ MacOsX
  • seq++
  • C++ Compiler 

:: DOWNLOAD

PANOW

:: MORE INFORMATION

Citation

N. Vergne and M. Abadi.
Poisson approximation for search of rare words in DNA sequences,
ALEA Vol. 4 pp. 223-244, 2008.

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