MMBPred – Predict Mutated MHC Binders

MMBPred

:: DESCRIPTION

 MMBPred is a server of prediction of of MHC class I binders which can bind to wide range of MHC alleles with high affinity. This server has potential to develop sub-unit vaccine for large population

::DEVELOPER

 MMBPred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Bhasin,M. and Raghava, G.P.S. (2003)
Prediction of promiscuous and high-affinity mutated MHC binders.
Hybrid Hybridomics.22(4),229-34.

BcePred – Predict B cell Epitope based on Physio-chemical Properties of Amino Acids

BcePred

:: DESCRIPTION

The BcePred server predicts B cell epitope based on physio-chemical properties of amino acids.

::DEVELOPER

BcePred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Saha.S and Raghava G.P.S.
BcePred:Prediction of Continuous B-Cell Epitopes in Antigenic Sequences Using Physico-chemical Properties.
In G.Nicosia, V.Cutello, P.J. Bentley and J.Timis (Eds.) ICARIS 2004, LNCS 3239, 197-204, Springer,2004.

MHC – Matrix Optimization Technique for Predicting MHC binding Core

MHC

:: DESCRIPTION

MHC server was used Matrix Optimization Technique to predict MHC binding core.

::DEVELOPER

G P S Raghava
,
:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Singh, H. and Raghava, G. P. S. (2002)
Detection of Orientation of MHC Class II Binding Peptides Using Bioinformatics Tools
Biotech Software and Internet Report, 3:146

SplamiR – Predicting miRNAs in Plants

SplamiR

:: DESCRIPTION

SplamiR is the first method for the prediction of spliced miRNAs in plants. It takes genomic sequence and the sequence of a potential target mRNA as input. In the first phase of SplamiR, a database of complementary sequence pairs is created for the given genomic sequence. These sequence pairs might encode for RNAs folding into stem-loop structures. In the second phase, this database is searched for sequences with complementarity to the given target mRNA. For the identified sequences, in silico splice variants are generated and these are classified as to whether they might represent pre-miRNAs.

::DEVELOPER

Theißen lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Java

:: DOWNLOAD

  SplamiR

:: MORE INFORMATION

Citation:

Bioinformatics. 2011 May 1;27(9):1215-23. doi: 10.1093/bioinformatics/btr132. Epub 2011 Mar 17.
SplamiR–prediction of spliced miRNAs in plants.
Thieme CJ, Gramzow L, Lobbes D, Theissen G.

PTMPred – Predict Post-transcriptional Modification sites from Protein sequences

PTMPred

:: DESCRIPTION

PTMpred is a tool for predicting post-transcriptional modification sites based on protein sequence.

::DEVELOPER

APORC

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux

:: DOWNLOAD

 PTMpred

:: MORE INFORMATION

Citation

Prediction of posttranslational modification sites from amino acid sequences with kernel methods.
Xu Y, Wang X, Wang Y, Tian Y, Shao X, Wu LY, Deng N.
J Theor Biol. 2014 Mar 7;344:78-87. doi: 10.1016/j.jtbi.2013.11.012.

Prodepth – Predict Residue Depth from Protein Sequences only

Prodepth

:: DESCRIPTION

Prodepth is an online prediction web server for the accurate prediction of residue depth from protein sequences only. It can be used to accurately identify the burial depth status of amino acid residues in a protein.

::DEVELOPER

Akutsu Laboratory , Whisstock Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

PLoS One. 2009 Sep 17;4(9):e7072. doi: 10.1371/journal.pone.0007072.
Prodepth: predict residue depth by support vector regression approach from protein sequences only.
Song J, Tan H, Mahmood K, Law RH, Buckle AM, Webb GI, Akutsu T, Whisstock JC.

RCDP – Performs Co-evolutionary Analysis of Domains in Interacting Proteins to Predict Domain Pair(s)

RCDP

:: DESCRIPTION

RCDP (Relative Co-evolution of Domain Pairs) tests the generality of the observed behavior, and to predict large-scale domain–domain interactions using the yeast inter-actome.

::DEVELOPER

Teresa Przytycka Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • perl 

:: DOWNLOAD

 RCDP

:: MORE INFORMATION

Citation

Raja Jothi et al.
Co-evolutionary analysis of domains in interacting proteins reveals insights into domain-domain interactions mediating protein-protein interactions
Journal of Molecular Biology, 29;362(4):861-75, 2006

JPREdictor 1.23 – Predict Cis-regulatory Elements

JPREdictor 1.23

:: DESCRIPTION

jPREdictor is a tool for the prediction of cis-regulatory elements, e.g. PRE/TREs in Drosophila melanogaster. Short sequence fragments, namely transcription factor binding sites, are known to be enriched and clustered in such elements. These binding sites are represented as motifs and for the prediction, they must be known. Using these motifs, it is possible to search them on sequences, to weight them by applying a positive or negative training set (model or background, respectively) and to score a sequence.

::DEVELOPER

Thomas Fiedler & Marc Rehmsmeier

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux / Mac / Windows
  • Java

:: DOWNLOAD

JPREdictor

:: MORE INFORMATION

Citation

Thomas Fiedler
The jPREdictor and its Application to Motif Discovery, Motif Clustering and the Prediction of Polycomb/Trithorax Response Elements
Dissertation, Univerity of Bielefeld, Apr 2008

Thomas Fiedler and Marc Rehmsmeier
jPREdictor: a versatile tool for the prediction of cis-regulatory elements
Nucleic Acids Research, 34:W546-W550, 2006

RNAcontext – Predict the Sequence and Structure Preferences of RNA-binding proteins

RNAcontext

:: DESCRIPTION

RNAcontext is a motif-finding algorithm to infer binding preferences of RNA binding proteins (RBP) from experimental affinity data. The input to RNAcontext consists of a set of sequences together with their associated structure annotation profiles (estimated using SFOLD) and RNA-binding affinity estimates for the given RBP. By learning a motif model that predicts the input affinities, RNAcontext infers the sequence and RNA secondary structure preferences of the RBP.

RBPmotif web server implements the RNAcontext algorithm and an additional analysis framework so that binding preferences of an RBP of interest can be identified from experimental data.

::DEVELOPER

Morris Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RNAcontext

:: MORE INFORMATION

Citation:

Nucleic Acids Res. 2013 Jul;41(Web Server issue):W180-6. doi: 10.1093/nar/gkt463. Epub 2013 Jun 10.
RBPmotif: a web server for the discovery of sequence and structure preferences of RNA-binding proteins.
Kazan H1, Morris Q.

H Kazan , D Ray, E Chan, TR Hughes, Q Morris (2010)
RNAcontext: a new method for learning the sequence and structure binding preferences.
PLoS Comput Biol 6(7): e1000832. doi:10.1371/journal.pcbi.1000832

FrameD 20070223 – Predict Coding Regions in Prokaryotic and Eukaryotic Sequence

FrameD 20070223

:: DESCRIPTION

FrameD is a program that predicts coding regions in prokaryotic and eukaryotic sequences that may contain frameshifts.

::DEVELOPER

Thomas Schiex

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows

:: DOWNLOAD

 FrameD

:: MORE INFORMATION

Citation

FrameD: a flexible program for quality check and gene prediction in prokaryotic genomes and noisy matured eukaryotic sequences
Thomas Schiex, Jérôme Gouzy, Annick Moisan, and Yannick de Oliveira
Nucl. Acids. Res. 2003 31: 3738-3741.

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