OsCAS (Oryza sativa Chips Annotation System) is a comprehensive system designed to annotate the results of rice microarray experiments and analysis relationships between genes based on their expression. The aim of the platform is to facilitate the study of differently expressed genes in the microarray experiments within the framework of systems biological research.
ArrayMining is a server for automating statistical analysis of gene and protein expression microarray data, designed as a supporting tool for investigation of the genetic components of diseases.
ReMoDiscovery is an intuitive algorithm to correlate regulatory programs with regulators and corresponding motifs to a set of co-expressed genes. It exploits in a concurrent way three independent data sources: ChIP-chip data, motif information and gene expression profiles.
GoSurfer uses Gene Ontology (GO) information to analyze gene sets obtained from genome-wide computations or microarray analyses. GoSurfer is a graphical interactive data mining tool. It associates user input genes with GO terms and visualizes such GO terms as a hierarchical tree. Users can manipulate the tree output by various means, like setting heuristic thresholds or using statistical tests. Significantly important GO terms resulted from a statistical test can be highlighted. All related information are exportable either as texts or as graphics.
RPS (Reproducibility Probability Score) computes reproducibility probability score to select differentially expressed genes. The Reproducibility Probability Score (RPS), takes into consideration both the replicated data in a particular lab and the measurement variability across labs. The measurement variability is assessed by utilizing the reference gene expression data generated in the Microarray Quality Control (MAQC) project. Specifically, we applied the data generated across replicate gene expression analysis that was conducted in multiple facilities as part of this effort. A larger RPS means a gene is more likely to be differentially expressed; and if similar transcription profiling measurements are made in other laboratories, it is highly likely to be confirmed.
Genetrix is an next-generation software that brings the full power of proven statistical methods, powerful machine-learning heuristics and integrated biological knowledge to the analysis and interpretation of gene expression, RNA, μRNA, SNP and DNA methylation microarray experiments.
DetectiV is a package for R containing functions for visualisation, normalisation and significance testing of pathogen detection microarray data. DetectiV uses simple and established methods for visualisation, normalisation and significance testing. When applied to a publicly available microarray dataset, DetectiV produces the correct result in 55 out of 56 arrays tested, an improvement on previously published methods.