GenCo 200806 – Estimate Gene Conversion and Crossover Rates

GenCo 200806

:: DESCRIPTION

GenCo is program to estimate gene conversion and crossover rates in population genetic data

::DEVELOPER

McVean Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 GenCo

:: MORE INFORMATION

Citation

Gay J, Myers S, and McVean G (2007).
Estimating meiotic gene conversion rates from population genetic data.
Genetics 177:881-94.

PEDEL – Estimate Diversity in Error-prone PCR Libraries

PEDEL

:: DESCRIPTION

PEDEL (Programme for Estimating Diversity in Error-prone PCR Libraries) can be used to calculate the expected number of distinct variants present in a library, given the library size, mean substitution rate and parent sequence length. On the web page, the user may produce plots of the expected number of distinct daughter sequences as a function of library size and substitution rate.

PEDEL Online Version

::DEVELOPER

Andrew Firth

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows / MacOsX
  • C++ Compiler
:: DOWNLOAD

  PEDEL

:: MORE INFORMATION

Citation

AndrewE. Firth, Wayne M. Patrick, 2005,
Statistics of protein library construction,
Bioinformatics, 21, 3314-3315.

TIMER 0.1 – Estimate Divergence Times

TIMER 0.1

:: DESCRIPTION

TIMER estimates the divergence times using linearized-tree approach. Compared with the program LINTREE (Takezaki et al. 1995), TIMER has more user-friendly interface. More importantly, TIMER can be used to estmate divergence times for concatenated or very large set of genes (proteins).

::DEVELOPER

Galina Glazko

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 TIMER

:: MORE INFORMATION

Citation:

Glazko, G. V. and M. Nei (2003)
Estimation of divergence times for major lineages of primate species.
Mol. Biol. Evol. 20:424-434.

PoooL 1.1 – Estimate Haplotype Frequencies from large DNA Pools

PoooL 1.1

:: DESCRIPTION

PoooL is a novel constrained EM algorithm to estimate frequencies of single-nucleotide polymorphism (SNP) haplotypes from DNA pools. A quantity called importance factor is introduced to measure the contribution of a haplotype to the likelihood. Under the assumption of asymptotic normality of the estimated allele frequencies and a system of linear constraints on haplotype frequencies the importance factor remains a constant in the iterative maximization process.

::DEVELOPER

Han Zhang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 PoooL

:: MORE INFORMATION

Citation

Han Zhang, Hsin-Chou Yang and Yaning Yang
PoooL: An efficient algorithm for estimating haplotype frequencies from large DNA pools
Bioinformatics 2008 24(17):1942-1948

 

ArrayOme 1.0 – Estimate the sizes of Microarray-visualised Bacterial Genomes

ArrayOme 1.0

:: DESCRIPTION

ArrayOme is a new software system to predict the size of the microarray-visualised genome (MVG) based on microarray-derived comparative genomic hybridization data.

::DEVELOPER

Hong-Yu Ou (tjohy@hotmail.com)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows

:: DOWNLOAD

 ArrayOme

:: MORE INFORMATION

Citation:

Hong-Yu Ou et al.
ArrayOme: a program for estimating the sizes of microarray-visualized bacterial genomes
Nucl. Acids Res. (2005) 33 (1): e3.

codonbias 20060818 – Estimate Selection Coefficients relating to optimal Codon usage

codonbias 20060818

:: DESCRIPTION

codonbias will allow the user to estimate selection coefficients relating to optimal codon usage. The basic methodology is similar to the codon based models implemented in the popular program PAML by Ziheng Yang. However, it explicitly models selection for optimal codon usage on different lineages of a phylogeny.

::DEVELOPER

the Nielsen group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 codonbias

:: MORE INFORMATION

HGT – Simulate and Estimate Horizontal Gene Transfer events

HGT

:: DESCRIPTION

HGT is a software to simulate and estimate Horizontal Gene Transfer events.

::DEVELOPER

 the Center of Integrative Bioinformatics Vienna (CIBIV) headed by Arndt von Haeseler.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 HGT

:: MORE INFORMATION

Citation:

Simone Linz, Achim Radtke, Arndt von Haeseler
A Likelihood Framework to Measure Horizontal Gene Transfer
Molecular Biology and Evolution, 24:1312-1319, 2007.

Mykiss 20100426 – Estimates Reproductive Success and Parentage using Genetic Data.

Mykiss 20100426

:: DESCRIPTION

Mykiss is a computer program for estimating the reproductive success of individuals based on genetic data (codominant genotypes).

::DEVELOPER

Steven Kalinowski, Ph.D.

:: SCREENSHOTS

::REQUIREMENTS

:: DOWNLOAD

 Mykiss

:: MORE INFORMATION

ML-NullFreq 200906 – Estimates the Frequency of Null Alleles at Microsatellite Loci

ML-NullFreq 200906

:: DESCRIPTION

ML-NullFreq  estimates the Frequency of Null Alleles at Microsatellite Loci.

::DEVELOPER

Steven Kalinowski, Ph.D.

:: SCREENSHOTS

N/A

::REQUIREMENTS

:: DOWNLOAD

  ML-NullFreq

:: MORE INFORMATION

Citation

Steven T Kalinowski, Mark L Taper
Maximum likelihood estimation of the frequency of null alleles at microsatellite loci
Conservation Genetics (2006) Volume: 7, Issue: Pages: 991-995

COB – Estimating Recombination Rates

COB

:: DESCRIPTION

COB is a parsimony-based method of computing likelihoods accurately under the coalescent with recombination.

::DEVELOPER

Rune Lyngsø

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 COB

:: MORE INFORMATION

Citation

Lyngsø, R., Song, Y.S., and Hein, J.
Accurate computation of likelihoods in the coalescent with recombination via parsimony.
Lect Notes Comput Sci. 2008; 4955(LNBI): 463–477.

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