ParsEval is a program for comparing two sets of gene structure annotations (provided as GFF3 files) for the same genomic region. Comparison statistics are calculated for each genic region, as well as for the entire region overall.
yrGATE (Your Gene structure Annotation Tool for Eukaryotes) is a web-based gene-structure annotation tool for the identification and dissemination of eukaryotic genes.yrGATE provides an Annotation Tool and Community Utilities for worldwide web-based community genome and gene annotation. Annotators can evaluate gene structure evidence derived from multiple sources to create gene structure annotations. Administrators regulate the acceptance of annotations into published gene sets. yrGATE is designed to facilitate rapid and accurate annotation of emerging genomes as well as to confirm, refine, or correct currently published annotations. yrGATE is highly portable and supports different standard input and output formats.
XRNA is a Java based suite of tools for the creation, annotation and display of RNA secondary structure diagrams.XRNA provides editing tools for easy modification of publication quality secondary diagrams that can be either drawn manually, or through automatic generation. Other features include grouping, numbering and structure annotation. XRNA secondary structures may be saved in a native format, or exported as postscript for printing and further manipulation in programs such as Adobe Illustrator.
STRAP, the Software Tool for Rapid Annotation of Proteins, saves you time by automatically annotating a protein list with information that helps you meaningfully interpret your mass spectrometry data.
BRAKER is a pipeline for unsupervised RNA-Seq-based genome annotation with GeneMark-ET and AUGUSTUS
TSEBRA (Transcript Selector for BRAKER) is a combiner tool that selects transcripts from gene predictions based on the support by extrisic evidence in form of introns and start/stop codons.
Gabriel L, Hoff KJ, Brůna T, Borodovsky M, Stanke M. TSEBRA: transcript selector for BRAKER.
BMC Bioinformatics. 2021 Nov 25;22(1):566. doi: 10.1186/s12859-021-04482-0. PMID: 34823473.
MAKER is a portable and easily configurable genome annotation pipeline. It’s purpose is to allow smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER is also easily trainable: outputs of preliminary runs can be used to automatically retrain its gene prediction algorithm, producing higher quality gene-models on seusequent runs. MAKER’s inputs are minimal and its ouputs can be directly loaded into a GMOD database.
fLPS is a package for the annotation of Compositional Biases (CB) regions, which includes added consideration of DNA sequences, to label the eight possible biased regions of DNA.
MINTIA is a software package enabling biologists to easily generate and analyze large metagenomic sequence sets, retrieved after activity-based screening. It filters reads, performs assembly, removes cloning vector, annotates open reading frames and generates user friendly reports as well as files ready for submission to international sequence repositories.