Guo-liang Fan and Qianzhong Li, Keli Yang,
TFBSs: a web server for Predicting transcription factor binding sites.
2012 IEEE International Conference on Cyber Technology in Automation, Control, and Intelligent Systems (CYBER), 2012,1:65-68
BSG is a collection of programs used to construct and analyze Binding Site Graphs. Overall,the analysis is a two step process that can be performed on separate computers. First, ensemble Gibbs sampling is performed, preferably on a massively parallel computer, and the results are collected. The resulting output files are then compressed (using gzip) to conserve disk space. Then, in a second step, the compressed output files are analyzed and predictions are made
SVMotif is a mechine learning based motif finder. It can be classified into K-mer enumeration based methods. the evaluation of each possible K-mer is done by Recursive SVM feature selection
RIP (regulatory interaction predictor) is a machine learning approach that inferred 73,923 RIs for 301 human TFs and 11,263 target genes with considerably good quality and 4,516 RIs with very high quality. The inference of RIs is independent of any specific condition.
MACO is a Position Frequency Matrix(PFM) comparing application that implements a gap-allowed alignment algorithm. You may compare your PFM with those collected in our dataset.
WordSpy is a novel, steganalysis-based approach for genome-wide motif finding. The software views regulatory regions as a stegoscript with cis-elements embedded in ‘background’ sequences. WordSpy can discover a complete set of cis-elements and facilitate the systematic study of regulatory networks.
LocalMotif is a software tool for discovering transcription factor binding motifs in a collection of DNA sequences. LocalMotif is based on a novel scoring function, called spatial confinement score, which can determine the exact interval of localization of a motif. This score is combined with other existing scoring measures including over-representation and relative entropy to determine the overall prominence of the motif. The approach successfully discovers biologically relevant motifs and their intervals of localization in scenarios where the motifs cannot be discovered by general motif finding tools. It is especially useful for discovering multiple co-localized motifs in a set of regulatory sequences, such as those identified by ChIP-Seq.