SVN – Remove Systematic Variation in Microarray Gene Expression data

SVN

:: DESCRIPTION

SVN (Systematic variation normalization) is a procedure for removing systematic variation in microarray gene expression data. Based on an analysis of how systematic variation contributes to variability in microarray data sets, the SVN procedure includes background subtraction determined from the distribution of pixel intensity values and log conversion, linear or non-linear regression, restoration or transformation, and multiarray normalization.

::DEVELOPER

Pierre R. Bushel, Ph.D.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows /MacOsX
  • Java

:: DOWNLOAD

 SVN

:: MORE INFORMATION

Citation:

Chou JW, Paules RS, Bushel PR.
Systematic variation normalization in microarray data to get gene expression comparison unbiased.
J Bioinform Comput Biol. 2005 Apr;3(2):225-41.

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