deNOPA – decoding Nucleosome Positions sensitively with Sparse ATAC-seq data

deNOPA

:: DESCRIPTION

deNOPA is a novel ATAC-seq analysis toolkit, to predict nucleosome positions.

::DEVELOPER

deNOPA team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

deNOPA

:: MORE INFORMATION

Citation

Xu B, Li X, Gao X, Jia Y, Liu J, Li F, Zhang Z.
DeNOPA: decoding nucleosome positions sensitively with sparse ATAC-seq data.
Brief Bioinform. 2021 Dec 7:bbab469. doi: 10.1093/bib/bbab469. Epub ahead of print. PMID: 34875002.

sparse.inv.cov 1.0.4 – Fitting very large Sparse Gaussian Graphical Models

sparse.inv.cov 1.0.4

:: DESCRIPTION

sparse.inv.cov is an R package designed for fitting large sparse covariance selection models.

::DEVELOPER

CSIRO Bioinformatics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • R

:: DOWNLOAD

 sparse.inv.cov

:: MORE INFORMATION

Citation

Harri Kiiveri, Frank de Hoog
Fitting very large sparse Gaussian graphical models
Computational Statistics & Data Analysis Volume 56, Issue 9, September 2012, Pages 2626–2636

glmgraph 1.0.3 – Graph-Constrained Regularization for Sparse Generalized Linear Models

glmgraph 1.0.3

:: DESCRIPTION

glmgraph is an R package for variable selection and predictive modeling of structured genomic data

::DEVELOPER

Li Chen <li.chen at emory.edu>

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R

:: DOWNLOAD

 glmgraph

:: MORE INFORMATION

Citation

glmgraph: An R Package for Variable Selection and Predictive Modeling of Structured Genomic Data.
Chen L, Liu H, Kocher JA, Li H, Chen J.
Bioinformatics. 2015 Aug 26. pii: btv497.

metagenomeSeq 1.34.0 – Statistical Analysis of Sparse High-throughput Sequencing data

metagenomeSeq 1.34.0

:: DESCRIPTION

metagenomeSeq is designed to determine features (be it Operational Taxanomic Unit (OTU), species, etc.) that are differentially abundant between two or more groups of multiple samples. metagenomeSeq is designed to address the effects of both normalization and under-sampling of microbial communities on disease association detection and the testing of feature correlations.

::DEVELOPER

HCBravo Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R
  • BioCOnductor

:: DOWNLOAD

  metagenomeSeq

:: MORE INFORMATION

Citation:

Nat Methods. 2013 Dec;10(12):1200-2. doi: 10.1038/nmeth.2658. Epub 2013 Sep 29.
Differential abundance analysis for microbial marker-gene surveys.
Paulson JN1, Stine OC, Bravo HC, Pop M.

SparseDC 0.1.17 – Sparse Differential Clustering

SparseDC 0.1.17

:: DESCRIPTION

SparseDC is an algorithm, which identifies cell types, traces their changes across conditions and identifies genes which are marker genes for these changes.

::DEVELOPER

Jun Li

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • MacOsX/  Linux / WIndows
  • R Package

:: DOWNLOAD

SparseDC

:: MORE INFORMATION

Citation

Nucleic Acids Res, 46 (3), e14 2018 Feb 16
A Sparse Differential Clustering Algorithm for Tracing Cell Type Changes via Single-Cell RNA-sequencing Data
Martin Barron , Siyuan Zhang , Jun Li

GFAsparse 1.0.3 – Elementwise Sparse Group Factor Analysis

GFAsparse 1.0.3

:: DESCRIPTION

GFAsparse implements the Bayesian Group Factor Analysis with element wise prior inducing sparsity.

::DEVELOPER

Probabilistic Machine Learning

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOS
  • R

:: DOWNLOAD

 GFAsparse

:: MORE INFORMATION

Citation

Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis.
Khan SA, Virtanen S, Kallioniemi OP, Wennerberg K, Poso A, Kaski S.
Bioinformatics. 2014 Sep 1;30(17):i497-i504. doi: 10.1093/bioinformatics/btu456.

SPONGE 1.8.0 – Sparse Partial Correlations On Gene Expression

SPONGE 1.8.0

:: DESCRIPTION

SPONGE provides methods to efficiently detect competitive endogeneous RNA interactions between two genes. Such interactions are mediated by one or several miRNAs such that both gene and miRNA expression data for a larger number of samples is needed as input.

::DEVELOPER

Baumbach lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows
  • R
  • Bioconductor

:: DOWNLOAD

SPONGE

:: MORE INFORMATION

Citation

Bioinformatics. 2019 Jul 15;35(14):i596-i604. doi: 10.1093/bioinformatics/btz314.
Large-scale inference of competing endogenous RNA networks with sparse partial correlation.
List M, Dehghani Amirabad A, Kostka D, Schulz MH

SCCA – Sparse Canonical Correlation Analysis

SCCA

:: DESCRIPTION

SCCA (Sparse Canonical Correlation Analysis) examines the relationships between two types of variables and provides sparse solutions that include only small subsets of variables of each type by maximizing the correlation between the subsets of variables of different types while performing variable selection. We also present an extension of SCCA – adaptive SCCA. We evaluate their properties using simulated data and illustrate practical use by applying both methods to the study of natural variation in human gene expression.

::DEVELOPER

David Tritchler

: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

   SCCA

:: MORE INFORMATION

Citation

Daniela M Witten and Robert J. Tibshirani
Extensions of Sparse Canonical Correlation Analysis with Applications to Genomic Data
Stat Appl Genet Mol Biol. 2009 January 1; 8(1): Article 28.

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