RIsearch 1.2 – Fast search for RNA-RNA interactions

RIsearch 1.2

:: DESCRIPTION

RIsearch is a program for fast RNA-RNA interaction search. It employs a modified Smith-Waterman-Gotoh algorithm based on di-nucleotides to approximate nearest-neighbor energy parameters.

::DEVELOPER

Center for non-coding RNA in Technology and Health (RTH)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RIsearch

:: MORE INFORMATION

Citation

Alkan F, Wenzel A, Palasca O, Kerpedjiev P, Rudebeck AF, Stadler PF, Hofacker IL, Gorodkin J.
RIsearch2: suffix array-based large-scale prediction of RNA-RNA interactions and siRNA off-targets.
Nucleic Acids Res. 2017 May 5;45(8):e60. doi: 10.1093/nar/gkw1325. PMID: 28108657; PMCID: PMC5416843.

Bioinformatics. 2012 Aug 24. [Epub ahead of print]
RIsearch: Fast RNA-RNA interaction search using a simplified nearest-neighbor energy model.
Wenzel A, Akbasli E, Gorodkin J.

SIM – Analyzing long-range RNA-RNA interactions in Viral Genomes and structured RNAs

SIM

:: DESCRIPTION

SilentMutations (SIM) can analyze the effect of multiple point mutations on the secondary structures of two interacting viral RNAs. It simulates destructive and compensatory mutants of two key regions from a single-stranded RNA, which can then be utilized for the combinatorial in vitro analysis of RNA-RNA interactions.

::DEVELOPER

RNA Bioinformatics and High Throughput Analysis Jena

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows
  • Python
  • numpy
  • viennaRNA

:: DOWNLOAD

SIM

:: MORE INFORMATION

Citation

D. Desiro, M. Hölzer, B. Ibrahim, and M. Marz,
SilentMutations (SIM): a tool for analyzing long-range RNA-RNA interactions in viral genomes and structured RNAs
Virus Res. 2019 Jan 15;260:135-141. doi: 10.1016/j.virusres.2018.11.005. Epub 2018 Nov 12.

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