REGENT 1.0.5 – Calculate Risks Conferred by Genetic Factors and Multi-level Environmental Factors

REGENT 1.0.5

:: DESCRIPTION

REGENT (Risk Estimation for Genetic and Environmental Traits) is an R package to calculate risks conferred by genetic factors and multi-level environmental factors.  This is performed at a population level, with the option to also analyse individual-level data.  REGENT incorporates variability in risk factors to calculate confidence intervals for risk estimates and to classify the population into different categories of risk based on significant differences from the baseline average member of the population.

::DEVELOPER

Professor Cathryn Lewis’ Group

:: SCREENSHOTS

N/A

::REQUIREMENTS

:: DOWNLOAD

 REGENT

:: MORE INFORMATION

Citation

Eur J Hum Genet. 2013 Jan;21(1):109-11. doi: 10.1038/ejhg.2012.107. Epub 2012 Jun 6.
REGENT: a risk assessment and classification algorithm for genetic and environmental factors.
Crouch DJ, Goddard GH, Lewis CM.

ALBERT – A Likelihood-Based Estimation of Risk in Trios

ALBERT

:: DESCRIPTION

ALBERT (A Likelihood-Based Estimation of Risk in Trios) is a C program that estimates genotype relative risks, genotyping error rates and population risk allele frequencies from marker genotype data in case-parent trios. ALBERT uses the distribution of trio marker genotypes to compute maximum likelihood estimates for the parameters. Complete instructions for running the program can be found in the documentation “albert.pdf” which can be downloaded here. Briefly, ALBERT runs on unix and requires two files, a marker file and a pedigree file (in LINKAGE format). The user must specify the names of these files on the command line, as well as the name of an output file that ALBERT will create. Finally, the user must specify one of the two available error models which are described in the documentation.

::DEVELOPER

Adele Mitchell at adele@u.washington.edu

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 ALBERT

:: MORE INFORMATION

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