Sunflower is an evolutionary model for promoters, analogous to the commonly used synonymous/nonsynonymous mutation models for protein-coding sequences.
HKA is a computer program that carries out the widely used statistical test for natural selection.This program can handle very large numbers of loci and sample sizes, and conducts tests via coalescent simulation as well as by the conventional chi square approximation. The simulations can also be used to conduct other tests of natural selection, including tests of Tajima’s D statistic (1989) and the D statistic of Fu and Li (1993).
INSIGHT is a method for inferring signatures of recent natural selection from patterns of polymorphism and divergence across a collection of short dispersed genomic elements.
BayeScan ( (BAYEsian genome SCAN for outliers) ) aims at identifying candidate loci under natural selection from genetic data, using differences in allele frequencies between populations. BayeScan is based on the multinomial-Dirichlet model. One of the scenarios covered consists of an island model in which subpopulation allele frequencies are correlated through a common migrant gene pool from which they differ in varying degrees. The difference in allele frequency between this common gene pool and each subpopulation is measured by a subpopulation specific FST coefficient. Therefore, this formulation can consider realistic ecological scenarios where the effective size and the immigration rate may differ among subpopulations
Is It Chance is a very simple little program that demonstrates the power of natural selection to accumulate favorable variations is anything but “mere chance.”.Is It Chance pits chance and selection against each other in a race to match a string of random letters to a sentence typed in by the user, and reveals clearly the difference between natural selection and “mere chance.”